Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
نویسندگان
چکیده
BACKGROUND To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected for analysis of IgM and IgG antibody seropositivity for CP and MP by enzyme-linked immunosorbent assay (ELISA). Comparison of the distribution of seropositivity of these antibodies among patients with wet and dry AMD, and controls was performed. A prospective comparative clinical trial was applied. RESULTS There was no major difference in the distribution of IgM and IgG seropositivity to CP and MP in patients with wet and dry AMD, and in controls (p > 0.05). CONCLUSIONS We found no significant association between MP as well as CP antibody titers and AMD. It seems that MP or CP infection is not a risk factor for AMD. KEYWORDS Mycoplasma pneumoniae; Chlamydia pneumoniae; Age-related macular degeneration; Serology.
منابع مشابه
Serological Association of Chlamydia pneumoniae Infection with Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis
BACKGROUND We investigated the serological association of Chlamydia pneumoniae infection with age-related macular degeneration (AMD). METHODS A systematic review and meta-analysis was performed. PubMed, Embase, Web of Science and the Association of Research in Vision and Ophthalmology abstracts were searched to identify studies investigating the serological association of Chlamydia pneumoniae...
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